(f) Western blot and its quantification showing protein levels of astrocyte (GLUL and GFAP) and microglia (IBA1 and MMP9) enriched genes in control (ctrl) and terminal prion disease (PrD) samples (*p<0.05; **p<0.01; ***p<0.001; two-tailed t test comparing terminal PrD vs ctrl samples; error bars: standard deviation). The gene discussed is AIF1; the disease is X-linked retinal dysplasia.