BRCA1 and breast cancer: Among them, 10% variants were detected in BRCA1 and BRCA2. This frequency was comparable with other high frequencies of pathogenic BRCA1/2 variants reported in other studies conducted in young Africans (Awadelkarim et al., 2007; Cherbal et al., 2010), Caucasians (Copson et al., 2018; De Sanjosé et al., 2003; Tonin et al., 2001), or African American women with breast cancers (Haffty et al., 2009; Malone et al., 2006; Table 4).