Regarding CD99 and CSF2RA located in PAR1, a recent study using the same data set used herein GSE46687), investigating DEGs between X monosomy TS patients and healthy women, reported that CD99 and CSF2RA were downregulated, thus, potentially increasing the frequency of autoimmune diseases among women with TS (Wang et al., 2020). Here, CD99 is linked to autoimmune disease.