CEACAM5 and liver disorder: Kurilova et al. have shown that in mCRC patients in the salvage setting, 1-year OS can range from 10% to 90% based on independent baseline parameters (number of extra-hepatic disease sites, carcinoembryonic antigen, albumin, alanine aminotransferase level, tumour differentiation level and the sum of the two largest tumour diameters) [38].