DHCR24 has been associated with multiple cellular functions, such as oxidative stress reduction, neuroprotection, anti-apoptotic function, and anti-inflammatory activity.34,35 Interestingly, the expression of DHCR24 is upregulated in various tumours.36,37,49 In the present study, we firstly discovered that the expression of DHCR24 was significantly downregulated in GD-treated Hep3B cells, as measured by microarray assays. The gene discussed is DHCR24; the disease is neoplasm.