Meanwhile, recent reports demonstrated that in hepatitis C virus (HCV)-related HCC, overexpression of DHCR24 was induced by HCV, which indicated that DHCR24 could be a valuable therapeutic target for HCV-related HCC.50,51 In our study, we tested two HBV-related HCC cell lines and found that the expression of DHCR24 was upregulated in all of them compared to the normal liver cell line. Here, DHCR24 is linked to hepatocellular carcinoma.