HLA-A and colorectal carcinoma: A significant negative correlation (Pearson’s r = −0.15, p < 0.001) was observed between cMS mutation frequency and the likelihood of HLA-A*02:01 ligands resulting from the respective cMS mutation in the HLA-A*02:01-positive but not in the HLA-A*02:01-negative group of MSI CRC (Fig. 5a).