Considering that KLF family members have been reported to have various effects on vascular endothelial cells and tumor-associated angiogenesis [29, 33, 34], we speculated that KLF12 might play a critical role in SCLC angiogenesis and that miR-141 promotes neovascularization via KLF12. Here, KLF12 is linked to small cell lung carcinoma.