Finally, deficit schizophrenia is associated with the total paraoxonase 1 (PON1) status, namely a higher frequency of the Q allele and QQ genotype of the Q192R polymorphism in association with lowered activity of PON1 paraoxonase, an enzyme with anti-oxidative, anti-inflammatory, and antibacterial properties [14]. The gene discussed is PON1; the disease is schizophrenia.