A transgenic nude-mouse model, in which the nestin promoter drives GFP expression and labels nascent blood vessels with GFP within tumors [39] (Figure 7), was used to visualize angiogenesis, along with FUCCI imaging, which demonstrated that cycling cancer cells are located near tumor vessels and quiescent cancer cells are located far from tumor vessels (Figure 7) [8,9]. This evidence concerns the gene NES and cancer.