The lncRNA LERFS (Lowly Expressed in Rheumatoid Fibroblast-like Synoviocytes) is expressed at low levels in fibroblast-like synoviocytes (FLSs) derived from patients suffering for rheumatoid arthritis (RA) and regulates the migration, invasion, and proliferation of FLSs through interaction with the RBP SYNCRIP (a.k.a. hnRNPQ) [47]. The gene discussed is SYNCRIP; the disease is rheumatoid arthritis.