SLC16A1 and colorectal adenocarcinoma: Koukourakis et al. demonstrated in colorectal adenocarcinoma that CAFs expressed high levels of proteins involved in lactate absorption, Monocarboxylate Transporter 1 (MCT1) and Monocarboxylate Transporter 2 (MCT2), as well as high levels of lactate dehydrogenase 1 (LDH1), an enzyme that catalyzes lactate oxidation.