Basal LH values >0.6 IU/L, especially peak LH values >5 IU/L and peak LH/FSH values >0.6 have been used to support the diagnose of CPP.[2] Pelvic B ultrasound showed the presence of ovarian follicles with diameters ≥0.4 cm. The gene discussed is BRD2; the disease is central precocious puberty.