In terms of bulk RNA-seq data, PD1, PDL1 and PDL2 were highly expressed in MC1 GBM patients whereas CTLA4, CD80 and CD86 were highly expressed in MC2 GBM patients in both the TCGA database (Figure 6B) and CGGA database (Figure 6C). The gene discussed is PDCD1; the disease is glioblastoma.