MAPT and semantic dementia: Our group has previously shown that over‐expression of P‐tau leads to an increase in AChE expression in the brain of Tg‐VLW mice expressing 3 missense mutations of human tau (G272V‐P301L‐R406W) associated with the autosomal dominantly inherited frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP‐17) (Silveyra, et al., 2012).