The statistical analyses linking PTPRG to risk of ischemic vascular disease (Figure 7A–C) and reduced left ventricular ejection fraction (Figure 7D) were all adjusted for sex, age, body mass index, genetic principal component, smoking status, dyslipidemia, diabetes, and hypertension between carriers and non-carriers of the evaluated PTPRG variants. This evidence concerns the gene PTPRG and metabolic syndrome.