NTRK2 and Obesity: The two cell types also expressed Bdnf (ESμ=0.91, ESμ=0.99); mutations in BDNF and its receptor, NTRK2, is a known cause of monogenic obesity in humans and, in mice, BDNF signaling is required for normal energy homeostasis and glucoregulatory control (Kamitakahara et al., 2016).