The overall meta-analysis indicated that the OPG SNP T950C was associated with increased CAD risk in recessive (OR 1.46, 95% CI 1.15–1.85, P=0.002), CC vs TT (OR 1.54, 95% CI 1.18–2.01, P=0.001), and allelic (OR 1.21, 95% CI 1.07–1.39, P=0.002) models (Figures 2 and 3, and Table 3). The gene discussed is TNFRSF11B; the disease is coronary artery disorder.