TGFB1 and renal fibrosis: Reviewing the works about properties and effects of curcumin on urinary system disclosed the role of curcumin in prevention of renal fibrosis through deactivation of TGF-b1-induced epithelial mesenchymal transition process in tubular cells by affecting the snail-1, different interleukins (ILs), and matrix metalloproteinases (MMPs) [20,26].