Upon 3 consecutive passages in culture, the SiHa‐NF‐YA and C33A‐NF‐YA cells generated tumorspheres with a higher efficiency of maintenance than that in GFP cells (Figure 3C, P < 0.01), indicating that the overexpression of NF‐YA in cervical cancer cells improved the self‐renewal capacity. This evidence concerns the gene NFYA and cervical cancer.