In a recent review, Conrad et al24 summarized five mechanisms in which ADAM8 involved in cancer progression as follows: forming the pro‐tumorigenic microenvironment, dissociating ECM components, producing chemical resistance and modulating the extracellular activity of MMPs (matrix metalloproteinases), regulating cell motility and adhesion and inducing the formation of new blood vessels. Here, ADAM8 is linked to cancer.