SLC1A3 and brain disorder: So far, five different brain disorders have been associated with SLC1A3 mutations: EA (Jen et al., 2005; de Vries et al., 2009; Choi et al., 2017a; Iwama et al., 2018), migraine (Kovermann et al., 2017); Tourette syndrome (Adamczyk et al., 2011), attention-deficit hyperactivity disorder and autism (van Amen-Hellebrekers et al., 2016).