Previously, Moolenaar et al. obtained the abnormally elevating N,N-dimethylglycine (DMG) induced by the congenital deficiency of enzyme dimethylglycine dehydrogenase (DMGDH) through 13C NMR spectroscopy and gas chromatography-mass spectrometry, which resulted in body odor [44]. The gene discussed is DMGDH; the disease is hyperinsulinemic hypoglycemia, familial, 4.