For example, antagomiRs or recombinant adenoviruses targeting miR-24 improve the recovery of cardiac function in myocardial infarction mice, by modulating the pathway involving endothelial nitric oxide synthase, the endothelial cell transcription factor GATA-2, and the serine/threonine protein kinase PAK4 [13]. Here, PAK4 is linked to myocardial infarction.