Using the training and validation datasets, we first identified 6 preserved PCa-driven modules and then screened 9 prognosis-related genes (including 3 lncRNAs: DLG5-AS1, MAGI2-AS3, and RHPN1-AS1; and 6 mRNAs: GINS2, NLGN2, EBNA1BP2, MELK, EIF5AL1, and G6PC3) from these modules to construct the risk score. Here, PDS5B is linked to posterior cortical atrophy.