There are many causes for low magnesium levels in diabetes, which include low magnesium diet, osmotic diuresis, which leads to high renal excretion of magnesium, insensitivity to insulin, which affects intracellular magnesium transport and causes increased loss of extracellular magnesium, usage of loop and thiazide diuretics, which promote magnesium wasting, diabetic autonomic neuropathies, and reduced tubular reabsorption due to IR (11). Here, INS is linked to diabetes mellitus.