EZH2 and cancer: The other mechanism of curcumin to chemosensitization of cancer cells is the up-regulation of microRNAs (miRNAs) involving in epithelial-mesenchymal transition and down-regulation of transcription factors B lymphoma Mo-MLV insertion region 1 homolog (BMI1), polycomb protein SUZ12, and enhancer of zeste homolog 2 (EZH2) (65).