This equation clearly demonstrated that APCDD1L, GREM1, GJB6, MZB1, RAP1GAP, PAEP, and MIXL1 constituted risk factors for ccRCC prognosis (coefficient > 0), while ADGRV1, POU2AF1, and PPARGC1A constituted protective factors (coefficient < 0). The gene discussed is MIXL1; the disease is nonpapillary renal cell carcinoma.