IGF1 and ischemia: However, the quantity of GFAP+/IGF-1+ double-positive cells in the infarct area increased following infusion of MSCs (Figures 3(i)–3(l)) from 24.47 ± 6.17/view field in the ischemia vehicle group to 31.03 ± 5.22/view field (p < 0.01) in the MSC group.