Finally, the trend for an association between the GG/AG genotype of rs7208505 in SKA2 and TESI in the unadjusted analysis (OR = 1.65, 95% CI = [0.97; 2.80]; p-value = 0.07; model 0, Table 2) became significant after adjustment for potential cofounders (OR = 1.81, 95% CI = [1.02; 3.19]; p-value = 0.04; model 1, Table 2) and also for depression severity changes (OR = 1.85, 95% CI = [1.03; 3.33]; p-value = 0.04; model 2, Table 2). The gene discussed is SKA2; the disease is depressive symptom measurement.