To verify whether PADI2 knockdown enhanced Olaparib's anticancer effect by inhibiting the invasion ability of A2780 and SKOV3 ovarian cancer cells, matrigel was prepared at the bottom of transwell chamber to compare the differences in the number of low PADI2 expression SKOV3-shPADI2 cell lines and A2780-shPADI2 cell lines with the control cells. Here, PADI2 is linked to ovarian cancer.