Given the profibrotic effect of TGF‐β1 and the role of ICAM‐1 in initiating the inflammatory process, the increased shear stress––in combination with increases in hoop stress––may play a significant role in progression of glomerulopathy in the remaining glomeruli in severe renoprival conditions. This evidence concerns the gene TGFB1 and lipoprotein glomerulopathy.