CFTR and cystic fibrosis: Cystic fibrosis transmembrane conductance regulator gene (CFTR) (OMIM: 602421) defect can cause CF (Zielenski & Tsui, 1995), and Cystic Fibrosis Mutation Database (CFMDB) (https://www.genet.sickkids.on.ca/cftr/app) has been established.