The genes coding for the TRAIL receptors are TNFRSF10A, TNFRSF10B, TNFRSF10C, and TNFRSF10D. The rs1047266 polymorphism of TNFRSF10B was found in a higher percentage of patients with MS than individuals without the disease. The gene discussed is TNFRSF10B; the disease is myeloid sarcoma.