However, shortly after NEBD, some of these transcripts are not translated at the same level between YF and AF oocytes, such as Sgk1, Aire, Castor1 and Eg5. These differences in translation result in different protein expression which in turn lead to chromosome misalignments and cytokinesis abnormalities in AF oocytes. Here, CASTOR1 is linked to atrial fibrillation.