CircFoxp1 is a 587 bp circular RNA consisting of Foxp1 exons 8–11 and is involved in mesenchymal stem cell differentiation and hepatocellular carcinoma cell proliferation and metastasis8,12, We here found that circFoxp1 recruited DNMT1 by binding to its host gene Foxp1 promoter. This evidence concerns the gene FOXP1 and hepatocellular carcinoma.