IDH1 and acute myeloid leukemia: AML patients with IDH1 mutation more often had a history of CAD compared to IDH1/2wildtype patients (26.1% vs. 6.4%; p = 0.002) and tended to present with a higher percentage of cardiovascular risk factors (26.1% vs. 10.1% p = 0.06) and valvular disease (13.0% vs. 3.8%, p = 0.32) than AML patients with IDH1/2wildtype (Fig. 2 and Table 2).