To assess whether the IDH mutation status in AML patients has an impact on cardiac function, we analyzed left ventricular ejection fraction (LVEF) by echocardiography in the control group (AML patients without IDH mutation) and the exposed group (AML patients with IDH1/2 mutation) before and at different time points during or after AML therapy. The gene discussed is IDH1; the disease is acute myeloid leukemia.