Of note, this is consistent with findings in human colon adenocarcinomas that also exhibit elevated Ubc9 protein expression [34] and almost twofold increases in median transcript levels in tumors (n = 275) compared to non-tumor (n = 349) tissues (GEPIA database, http://gepia.cancer-pku.cn/index.html, queried for UBE2I (Ubc9)) [35]. This evidence concerns the gene UBE2I and neoplasm.