Exosomes carry functional cargo in the form of proteins, nucleic acids and lipids, and we have previously reported that sarcoidosis BALF exosomes induce IFNγ in PBMCs and IL-8 in epithelial cells4, suggesting a role for sarcoidosis exosomes in T-cell activation and cell recruitment. The gene discussed is CXCL8; the disease is sarcoidosis.