dTAGV-1 led to a decrease in downstream EWS/FLI targets such as NKX2-2, and Gene Set Enrichment Analysis (GSEA) of the differentially regulated target proteins (FDR < 0.05) identified known EWS/FLI and Ewing sarcoma signatures (Fig. 3c–e). This evidence concerns the gene FLII and Ewing sarcoma.