TNFSF11 and ischemic cardiomyopathy: In multivariate analysis (cf Table 4), and after exclusion of highly influential observations, progression of lower limb arterial calcification was associated with (β coefficient [slope], 95% CI, p-value) baseline log calcification score (1.02, 1.00–1.04, p < 0.001), duration of follow up (0.04, 0.01–0.06, p = 0.004), ischemic cardiomyopathy (0.36, 0.15–0.57, p = 0.001), statin use (0.39, 0.06–0.72, p = 0.023), triglycerides (0.11, 0.03–0.20, p = 0.007) and log RANKL (0.07, 0.02–0.11, p = 0.016).