In a pre-clinical model, where Wilms tumour gene 1 peptide (122–140) and CpG adjuvant was administered by tattooing in combination with i.p injected anti-TGFβ mAb 1D11, an antitumour effect could be observed, with significantly retarded tumour growth of TRAMP-C2-induced tumour cells after 32 days compared to control mice that received PBS [139]. Here, TGFB1 is linked to neoplasm.