MTOR and cancer: Additionally, another set of lncRNAs, such as FAM201A, sensitize the cancer cells towards radiation therapy in ESCC via targeting cyclin-dependent kinase subunit 1 (Cks1), cyclin D1, Mammalian target of rapamycin (mTOR) and activating Non-homologous end joining (NHEJ) pathway [13] thereby enhancing the radiosensitivity of cancer cells.