Validating the role of LINC00473 in association with miR-374a-5p and miR-497-5p in ESCC radioresistance, these researchers observed enhanced cell viability, colony survival, PARP, and CdC25A protein expression levels in miR-374a-5p and miR-497-5p knockdown in ESCC cell [14,15]. This evidence concerns the gene PARP1 and esophageal squamous cell carcinoma.