In order to better understand the mechanisms of the MALAT1 in regulating radiosensitivity in ESCC cells, the authors identified cyclin-dependent kinase subunit 1 (Cks1) and Yes-associated protein (YAP) oncogenic transcriptional factor as the potential targets of MALAT1 (Figure 3, Table 1). The gene discussed is CKS1B; the disease is esophageal squamous cell carcinoma.