DNM3OS and esophageal squamous cell carcinoma: In addition, the dose enrichment ratio in KYSE-30 and KYSE-40 cultured in CAF containing condition-media was 3.3015 and 1.8368, respectively, compared to the control (standard medium), which confirmed the association of CAFs in modulating the expression of DNM3OS expression and thereby conferring radioresistance in ESCC [12].