This observation was further corroborated by generating a retina-specific Ahr knockout mouse model, which exhibited late-onset retinal degeneration, a decline in visual function, a reduction in photoreceptor cells, and an increase in apoptotic cell death in the retina, suggesting that Ahr is a candidate gene for the pathogenesis of RP [112]. The gene discussed is AHR; the disease is retinitis pigmentosa 1.