According to Zhang et al. [6], HFD induced hyperlipidaemia affected activity and the expression of hepatic enzymes, such as alcohol dehydrogenases (ADHs), retinol dehydrogenases (RDHs) and retinal dehydrogenases (RALDHs), which reduced plasma retinol levels. The gene discussed is SDR9C7; the disease is hyperlipidemia.