Moreover, selected ABO polymorphisms influence ACE inhibitors treatment response [28–30], and might contribute in reducing SARS-CoVs’ transmission, as reported by Guillon et al. [9], who ascribed to blood group O a lower risk of infection, hypothesizing that natural anti-A and anti-B antibodies can contribute in protecting against viral diseases at the population level. The gene discussed is ABO; the disease is viral infectious disease.