To analyse the functions of lincFOXF1 in osteosarcoma cells, we overexpressed or down‐regulated lincFOXF1 expression in MNNG‐HOS and 143B cells through transfection with the pcDNA3.1‐lincFOXF1 vector or lincFOXF1‐specific siRNA, respectively. The gene discussed is FENDRR; the disease is osteosarcoma.