This results indicates that (i) both miR-124 and BDNF can be a promising novel biomarker of ischemic stroke, (ii) miR-124 and BDNF could be a predictors of stroke severity, and (iii) inhibitor of miR-124 could be used as a potential approach for increasing BDNF serum levels [111]. Here, BDNF is linked to ischemic stroke.