Neutrophils, resting mast cells, M2 macrophages, M0 macrophages, resting natural killer cells, regulatory T cells, activated memory CD4+ T cells, resting memory CD4+ T cells, and CD8+ T cells were significantly different among molecular subgroups of NSCLC (P < 0.05). The gene discussed is CD8A; the disease is non-small cell lung carcinoma.