To investigate whether FZD10 mediated FASN-induced radiation resistance in NPC cells, we transiently overexpressed ectopic FZD10 (pcDNA3.1-FZD10) in CNE1-shRNA-FASN cells to rescue the expression of FZD10, which was reduced by FASN knockdown. The gene discussed is FASN; the disease is nasopharyngeal carcinoma.