Nylund et al., (2017) evaluated the association of the Salivary TREM-1 (sTREM- 1)/its Ligand Peptidoglycan Recognition Protein 1 (PGLYRP1) in periodontitis patients with renal diseases and concluded that PGLYRP1 and sTREM-1 are strongly associated with increased proinflammatory cytokine production in patients with periodontitis [183]. The gene discussed is PGLYRP1; the disease is periodontitis.